Khloe Kardashian Gets 'Punk'd' by Miley Cyrus and Kelly Osbourne (Video)

Khloe Kardashian falls prey to a prank orchestrated by Miley Cyrus and Kelly Osbourne in a sneak peek of MTV's Punk'd reboot.

Instead of featuring one host like the previous incarnation of the show, which starred Ashton Kutcher and his collection of trucker hats, the reboot is going to feature a variety of celebrity hosts. Justin Bieber already made headlines for playing a prank on poor Taylor Swift, and Dax Shepard and Kellan Lutz are also set to get their prank on when the show returns on March 19.

However, it's the ladies who get to have all the fun in the clip released by MTV. In the sneak peek, Miley Cyrus and Kelly Osbourne invite Khloe Kardashian over for a girls' night in. However, she's in for quite a shock after the delivery guy bringing their food uses Miley's restroom - he ends up with a very sensitive part of his anatomy stuck in his pants zipper, and Khloe is the one who calls 911 to get him help.

Khloe manages to keep her cool throughout the situation, even when she informs the faux delivery guy that he could lose a testicle.

The group of celebrity gals in the video are real-life pals - Miley Cyrus and Kelly Osbourne are obviously friends after the way Kelly stood up for Miley during weed-gate (when the singer was filmed jokingly saying that she's a pothead during her birthday party), and Kelly probably became buds with Khloe since they both have E! shows. So it will be interesting to see who some of the other celebrity hosts prank on Punk'd - maybe Kellan Lutz will pull a fast one on his Twilight costars Robert Pattinson and Kristen Stewart, or perhaps Dax Shepard will prank his longtime ladylove Kristen Bell. It would also be rather hilarious if the show tried to punk Ashton Kutcher, and who better to go after the former host than Charlie Sheen?

And of course Khloe Kardashian would probably love to be on the other end of the prank - maybe she could take her sister Kim Kardashian on the double date from hell.

So who else would you like to see get punk'd when the show returns? Check out Miley, Khloe, and Kelly on the show in the video below.